All Articles Tagged As: actin
The proteins actin, myosin and titin are big players in the business of muscle contraction. Scientists at the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, have now examined another muscle protein -- myomesin -- which they discovered can stretch up to two-and-a-half times its length, unfolding in a way that was previously unknown. The study is published Feb. 14 in the open-access, online journal PLoS Biology.
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A Jackson Laboratory research team led by Professor Patsy Nishina, Ph.D., has identified a mutation in a gene that's essential for correct protein-processing in cells. Defects in protein folding are associated with a variety of abnormalities and diseases.
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 | Researchers who developed a method for observing nanosecond-scale movements of proteins have used it to distinguish two structural forms where only one was known. The experiments described in PNAS focused on HP35 in the protein villin, which contributes to cells' stability by linking actin filaments. More generally, the results suggest that this method, based on fast electron transfer between different parts of a protein, could help unlock the mechanisms behind folding and misfolding of proteins. ...> Full Article |
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