Proteomics News - April 2011 Archives
 | JBEI researchers have demonstrated a new technique that speeds up and improves the identification and quantification of proteins within a cell or micoorganism. Called "targeted proteomics," the new technique is expected to be an important new tool for the fields of metabolic engineering and synthetic biology. ...> Full Article |
 | In two new studies, researchers provide the first detailed view of the elaborate chemical and mechanical interactions that allow the ribosome -- the cell's protein-building machinery -- to insert a growing protein into the cellular membrane. The first study gives an atom-by-atom snapshot the moment just after the ribosome docks to a channel in the membrane and the newly forming protein winds its way into the membrane. The second study found that proteins get inserted into the membrane in two stages. ...> Full Article |
By harnessing the unique properties of polarized light, Rockefeller scientists have developed a new technique that can help deduce the orientation of specific proteins within a cell.
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By identifying a surprising association of two intracellular proteins, University of Iowa researchers have laid the groundwork for the development of new therapies to treat B cell lymphomas and autoimmune disease.
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Researchers at Johns Hopkins have discovered in mice a molecular wrecking ball that powers the demolition phase of a cycle that occurs at synapses -- those specialized connections between nerve cells in the brain -- and whose activity appears critical for both limiting and enhancing learning and memory.
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In the constantly morphing field of protein structure, scientists at the Scripps Research Institute offer yet another surprise: a common "chaperone" protein in cells thought to help other proteins fold has been shown instead to loosen them.
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Pitt and Stanford researchers report in the Proceedings of the National Academy of Sciences that a supposedly inactive protein actually plays a crucial role in the ability of one the world's most prolific pathogens to cause disease and could also be important to other such pathogen-based diseases as malaria.
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